ABSTRACT
OBJECTIVE To investigate the distribution and drug resistance of strains producing extended spectrum beta-lactamases (ESBLs) isolated from clinic samples and offer scientific basis for reasonable usage of antibioticsMETHODS ESBLs-producing strains isolated from Escherichia coli were identified by phenotypic comfirmatory test,drug resistance was analyzed by K-B method. RESULTS The positive rate of isolated ESBLs-producing E. coli strains was respectively 18.0%,20.3% and 28.4% in three years; that of ESBLs-producing strains isolated from urinary system was respectively 25.6%,29.0% and 39.0% in three years. The susceptibility to AMK and CFS was 70.4% and 85.2%,respectively in 2006. CONCLUSIONS The positive rate of ESBLs-producing strains and their resistance have been increasing in the near three years. so our clinic should pay attention to reasonable usage of antibiotic. AMK and CFS show significant antimicrobial activity for ESBLs-producing E. coli.
ABSTRACT
@#Objective To investigate the risk factors of cerebral palsy(CP)in children.Methods 1∶2 matched case-control study was carried out in 100 CP children and 200 controls individually matched for sex and age were selected for each case.The data were analyzed with Logistic regression.Results 9 risk factors were suggested from univariate analysis,namely hospital level,educational level of mother and father,premature birth,neonatal asphyxia,ABO hemolysis,lower birth weight,hypoxic-ischemic encephalopathy(HIE)and kernicterus.The risk factors confirmed by multivariate analysis were hospital level,educational level of father,premature birth,neonatal asphyxia,ABO hemolysis,lower birth weight and HIE.Conclusion Relevant risk factors of CP are various.